PHOTOREVERSAL OF ULTRAVIOLET-INDUCED MUTAGENIC AND LETHAL EFFECTS IN ESCHERICHIA COLI
نویسندگان
چکیده
منابع مشابه
Lethal and mutagenic effects of ultraviolet radiation on Glomerella conidia.
IN comparative studies of the mutagenic action of ionizing and ultraviolet radiation on conidia of the fungus Glomerella (5) it was evident that the shape of the mutation curve was different for the two types of radiation. The dose-mutation curve for the surviving spores was essentially linear for the ionizing radiations, but with the ultraviolet radiation the mutation curve rose with increasin...
متن کاملBacterial and mammalian DNA alkyltransferases sensitize Escherichia coli to the lethal and mutagenic effects of dibromoalkanes.
Here we confirm and extend our previous studies demonstrating that the mutagenic potency of 1,2-dibromoethane (DBE) and dibromomethane (DBM) is markedly enhanced (not prevented) in bacteria expressing the O6-alkylguanine-DNA alkyltransferase (ATase) encoded by the Escherichia coli ogt gene. We demonstrate that, in close parallel with mutagenesis, the Ogt ATase sensitizes the bacteria to the let...
متن کاملUVM, an ultraviolet-inducible RecA-independent mutagenic phenomenon in Escherichia coli.
Most mutagenic DNA lesions are noninstructive in the sense that template instruction is either missing or inaccessible during DNA replication, leading to replication arrest. According to the SOS hypothesis, arrested replication induces the expression of SOS factors that force replication past stalled sites at the cost of mutagenesis. We have recently shown that prior UV irradiation of delta rec...
متن کاملDouble mutations induced in Escherichia coli by ultraviolet light.
Double mutations to azide resistance and to bacteriophage T5 resistance of genes separated by more than 50 kilobases were induced in Escherichia coli WP2s in chemostat cultures by exposure to a single low dose of ultraviolet light. Frequencies of induced double mutations were three orders of magnitude greater than would be predicted by chance. Reversions from azide resistance and phage resistan...
متن کاملLethal effects of electric current on Escherichia coli.
An attempt has been made to use low-voltage alternating current to kill microorganisms such as Escherichia coli. The bactericidal effect depends on the energy passing through the suspension and on the time during which the cells are left standing in the medium after the treatment. Most of the toxicity is due to an indirect effect developed with unalterable electrodes in the presence of chloride...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1951
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.61.3.243-251.1951